SCS - AMPAlive Label P450 Drug Precaution

The precaution listed on the AMPAlive label, relates specifically to the ingredient Berberine. Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with BERBERINE.

Some medications are changed and broken down by the liver. Berberine might decrease how quickly the liver breaks down some medications. Taking berberine along with some medications that are broken down by the liver can increase the effects and side effects of some medications. 

Some medications changed by the liver include cyclosporin (Neoral, Sandimmune), lovastatin (Mevacor), clarithromycin (Biaxin), indinavir (Crixivan), sildenafil (Viagra), triazolam (Halcion), and many others.

Before taking berberine, talk to your healthcare provider if you are taking any medications that are changed by the liver.